In Scientific Plastic Products, Inc. v. Biotage, AB, the Federal Circuit Court of Appeals affirmed the decision of the Patent Trial and Appeal Board affirming the Patent Examiner’s rejection based on obviousness and the cancellation of all the claims in three patents.  The Federal Circuit found that the art relied upon in the obviousness rejection was analogous art and that there was a motivation to combine the references.  The opinion can be read here Scientific Plastic Products v Biotage